Cymbalta (Duloxetine) for Endometriosis

Overview
Cymbalta is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat major depressive disorder, generalized anxiety disorder, and chronic pain conditions including fibromyalgia. Cymbalta is sometimes prescribed off-label to treat symptoms of endometriosis. Cymbalta is also referred to by its drug name, duloxetine.

Cymbalta is a member of a class of drugs called serotonin and norepinephrine reuptake inhibitors. Serotonin and norepinephrine are brain chemicals that influence mood, emotion, sleep, and pain perception. Cymbalta is believed to work by keeping these chemicals available in the brain for a longer amount of time, which is thought to help relieve chronic pain.

How do I take it?
Prescribing information states that Cymbalta is taken orally once daily.

Cymbalta comes in capsule form.

Side effects
The FDA-approved label for Cymbalta lists common side effects including nausea, dry mouth, drowsiness, constipation, decreased appetite, and increased sweating.

Rare but serious side effects listed for Cymbalta include suicidality, liver toxicity, low blood pressure when standing up, mania, seizures, blood pressure increases, low blood sodium, severe skin reactions, and trouble urinating.

For more details about this treatment, visit:

Cymbalta — Eli Lilly
http://pi.lilly.com/us/Cymbalta-Medguide.pdf

Cymbalta — RxList
https://www.rxlist.com/cymbalta-drug.htm