I had read mostly negative reviews as I researched this "miracle pill". I decided to give in and try it. I was only able to hang in there for 9 weeks on the lower dose. It DID subside my endo symptoms within a few days & I didnt have a period. It ALSO gave me horrible headaches(near migraines) EVERY SINGLE DAY, I felt run down, I was always hot, emotionally i was borderline numb, I gained weight in a weird pooch pocket(I'm still trying to work out). For me, it wasnt worth it. I would rather have my horrid pain than feel that way every day. Within a week of stopping, I felt like "me" again.

Ive been on orillisa for a few months and after about 3 months my pain came back. I want to say I’m an oddball case but honestly, all of us are so who knows. Im starting the higher dosage or orillisa next week but honestly i dont think my doctor really knows what to do with me after that if my pain doesnt go away.
I believe that endo grows off of hormones like estrogen. So putting us in a medically induced menopause takes some of those hormones away, which “shrinks” the lesions. That being said, once we stop taking the pill they will start to grow again.

Have you had excision surgery?